Wednesday, August 26, 2020

The Exeter Book :: Old English Poetry Literature Essays

The Exeter Book The Exeter Book is the biggest existing assortment of Old English verse. The original copy was given to the library of Exeter Cathedral by its first cleric, Leofric, toward the finish of the tenth century. The book comprises of 131 material leaves which measure roughly 12.5 by 8.6 inches. The most well known works contained in the Exeter Book incorporate â€Å"The Wanderer,† â€Å"The Wife’s Lament,† â€Å"The Seafarer,† and â€Å"Wulf and Eadwacer.† notwithstanding the 31 significant sonnets, 96 puzzles are additionally remembered for the assortment. The composition was likely replicated by a solitary recorder in 975, however â€Å"The Wanderer† is however to go back to the Anglo-Saxon tribes’ change to Christianity in the 6th century. â€Å"The Wife’s Lament† may have pre-dated â€Å"The Wanderer† on the grounds that â€Å"it offers none of the regular Christian comfort for her despondency and seems to mirror a pre-transformation, agnostic mentality towards ones’ fate† (The Exeter Book). The two sonnets are significant assets in their portrayal of the statutes and jobs of people in Anglo-Saxon society. â€Å"The Wanderer† is a funeral poem, or a mourn for the dead and the wonders of the past. The storyteller of the sonnet has lost his kinfolk in fight and is meandering alone and examining the transient idea of life. Plainly the storyteller regards the comitatus, the obligation of faithfulness between a master and his warriors, as is delineated when he recalls â€Å"embracing and kissing his master ruler and laying his hands and his head on his knee† (Wanderer 101). The aloof mentality of the storyteller is intelligent of the Anglo-Saxon culture in which men should be fearless and dispassionate. Regardless of this show, the narrator’s distress is firmly passed on in the Ubi Sunt (‘Where are they?’) entry when he asks, â€Å"Where has the pony gone? Where the youthful warrior? Where is the provider of the treasure?† (Wanderer 101). The narrator’s regret additionally shows the penetrating social conviction that everything in life is fore ordained by destiny. This is seen when the storyteller imagines the apocalypse in everlasting winter when â€Å"all the earth’s realm is pitiful [and] the world underneath the skies is changed by crafted by the fates† (Wanderer 102). The sonnet closes with a solid reference to Christianity in the lines, â€Å"It will be well with him who looks for favor, comfort from the Father in paradise, where for every one of us dependability resides† (Wanderer 102).

Saturday, August 22, 2020

Squad Five-O - Bombs Over Broadway free essay sample

Rockin it, rockin it, at the apocalypse!Squad Five-Os lead artist Jeff Fortson yells in Apocalypse Now fromtheir new collection, Bombs Over Broadway. This phenomenal third effortoutdoes their dazzling introduction collection, What I Believe. Bombs Over Broadway was discharged by Squad Five-Os new mark, Tooth Nail Records, most popular for the band MxPx. For the individuals who have never heardof Squad Five-O, they are an absolutely magnificent and interesting musical gang impacted by70s and 80s punk and awesome. The title track of Bombs OverBroadway spellbinds the audience with its appealing guitar riffs and ensemble. Ifound myself chiming in the first occasion when I heard it. Another feature, WeRule the Night, flaunts the groups huge muscles, starting with adriving bass and musical drum beat, and transforming into a full scale party once theguitar and vocals come in. Different tracks I suggest remember the upbeatRenegade and Tramps for the Run, just as the slower,more melodic, Restless Youth. We will compose a custom paper test on Crew Five-O Bombs Over Broadway or on the other hand any comparative theme explicitly for you Don't WasteYour Time Recruit WRITER Just 13.90/page The band comprises of two pairsof siblings Jeff Fortson (lead artist and guitar) and John Fortson (bass andback-up vocalist), just as Adam Garbinski (guitar and back-up) and JustinGarbinski (drums). I prescribe this collection to fanatics of a stone or punkmusic in light of the fact that Squad Five-O realizes how to make some extraordinary memories and engage. Believeme when I state this collection is no mistake. The Zeus of all stone and-rollbands, Squad Five-O gives out more in-your-face sound than any other time in recent memory. Look at it.

Friday, August 21, 2020

User Interface Critique (Scenario) Example

User Interface Critique (Scenario) Example User Interface Critique (Scenario) â€" Assignment Example > Executive summaryA human computer interface is designed in such a manner that it appeals to the user in various ways. Such an interface is supposed to contain various features that appeal to the user in terms of user friendliness, goals destined for the user experience, design principles applied, heuristics and the usability goals. The “Nuclear Matters” exhibition at the powerhouse museum is a permanent exhibition that has been designed in such a manner that it helps people to learn all that nuclear science is about in an interactive manner. This exhibition has been divided into five areas which include the nuclear basics, nuclear in people’s lives such as in medicine and internal scanning of the body, nuclear science, nuclear power generation and the nuclear perspectives that have had an impact on the attitude of people in the 21st century. This paper looks at some of the interactive that are currently in the nuclear matters exhibition at the powerhouse museum. The paper wi ll look at two of the interactives and consequently critique their user interfaces. The critique will be stepwise and will focus on the principles of human computer interaction. Introduction“Nuclear matters” is a highly interactive exhibition that explores the nuclear science world and also incorporates nuclear power and medicine. The main purpose of nuclear matters is to provide a high public understanding of nuclear science and its functions to our daily lives. In nuclear matters, there is a revelation of the various radio active features in our daily lives. The forum ties to explain what radiation is and also tries to explain the logic behind production of radiations. The exhibition has tried to explain the various applications of nuclear technology from the diagnosis of medical problems to generation of power. The exhibition also displays the materials that can be used to shield workers from radiation, the various ways in which we can deal with nuclear waste and the applic ation of a nuclear suit. This exhibition has nine interactives which allow people to walk through the various aspects of the nuclear world in a very interesting way. One of the interactives allows the user to control a nuclear reactor from the touch of a knob. Another different interactive is for power generation. This one allows the user to pedal a stationery bike that in turn produces electrical energy which is then compared to other forms of energy such as nuclear, coal, gas and other renewable forms of energy. The “nuclear matters” exhibition is divided into five main areas which are Basics of nuclearNuclear in our daily livesNuclear sciencePower generationNuclear perspectivesIn this exhibition there are various interactives. One of the interactives shows scienticists studying ice cores and climatic change in Antarctica. Another interactive shows the use of radiotherapy where a real medical scanner is being used to produce some images of body tissues and the interior parts of the body. This interactive uses a dummy patient. Below are images of the medical scanner. The gamma ray scanner and the dummy patient

User Interface Critique (Scenario) Example

User Interface Critique (Scenario) Example User Interface Critique (Scenario) â€" Assignment Example > Executive summaryA human computer interface is designed in such a manner that it appeals to the user in various ways. Such an interface is supposed to contain various features that appeal to the user in terms of user friendliness, goals destined for the user experience, design principles applied, heuristics and the usability goals. The “Nuclear Matters” exhibition at the powerhouse museum is a permanent exhibition that has been designed in such a manner that it helps people to learn all that nuclear science is about in an interactive manner. This exhibition has been divided into five areas which include the nuclear basics, nuclear in people’s lives such as in medicine and internal scanning of the body, nuclear science, nuclear power generation and the nuclear perspectives that have had an impact on the attitude of people in the 21st century. This paper looks at some of the interactive that are currently in the nuclear matters exhibition at the powerhouse museum. The paper wi ll look at two of the interactives and consequently critique their user interfaces. The critique will be stepwise and will focus on the principles of human computer interaction. Introduction“Nuclear matters” is a highly interactive exhibition that explores the nuclear science world and also incorporates nuclear power and medicine. The main purpose of nuclear matters is to provide a high public understanding of nuclear science and its functions to our daily lives. In nuclear matters, there is a revelation of the various radio active features in our daily lives. The forum ties to explain what radiation is and also tries to explain the logic behind production of radiations. The exhibition has tried to explain the various applications of nuclear technology from the diagnosis of medical problems to generation of power. The exhibition also displays the materials that can be used to shield workers from radiation, the various ways in which we can deal with nuclear waste and the applic ation of a nuclear suit. This exhibition has nine interactives which allow people to walk through the various aspects of the nuclear world in a very interesting way. One of the interactives allows the user to control a nuclear reactor from the touch of a knob. Another different interactive is for power generation. This one allows the user to pedal a stationery bike that in turn produces electrical energy which is then compared to other forms of energy such as nuclear, coal, gas and other renewable forms of energy. The “nuclear matters” exhibition is divided into five main areas which are Basics of nuclearNuclear in our daily livesNuclear sciencePower generationNuclear perspectivesIn this exhibition there are various interactives. One of the interactives shows scienticists studying ice cores and climatic change in Antarctica. Another interactive shows the use of radiotherapy where a real medical scanner is being used to produce some images of body tissues and the interior parts of the body. This interactive uses a dummy patient. Below are images of the medical scanner. The gamma ray scanner and the dummy patient

Sunday, May 24, 2020

The Domestication History of Chickpeas

Chickpeas (Cicer arietinum or garbanzo beans) are large roundish legumes, that look rather like a large round pea with an interesting bumpy surface. A staple of Middle Eastern, African and Indian cuisines, the chickpea is the worlds second most widely grown legume after the soybean, and one of the eight founder crops of the origins of agriculture on our planet. Chickpeas store really well  and are high in nutritive value, although they are not very disease resistant, compared to other legumes. The wild version of chickpeas (Cicer reticulatum) is only found in parts of what is today southeastern Turkey and adjacent Syria, and it is likely that it was first domesticated there, about 11,000 years ago. Chickpeas were part of the culture that first developed farming on our planet, called the Pre-Pottery Neolithic period. Varieties Domesticated chickpeas (also called garbanzo beans) come in two main groups called desi and kabuli  but you can also find varieties in 21 different colors and several shapes. Scholars believe that the oldest variety of chickpea is the desi form;  Ã‚   desi are small, angular, and variegated in color. The desi likely originated in Turkey and was subsequently introduced into India where kabuli, the most common form of chickpea today, was developed. Kabuli have large beige beaked seeds, which are more rounded than desi. Domesticating Chickpeas The chickpea gained several very useful features from the domestication process. For example, the wild form of chickpea ripens only in the winter, while the domesticated form can be sown during the spring for summer harvest. Domestic chickpeas still grow best in winter when there is adequate water available; but during the winters they are susceptible to Ascochyta blight, a devastating disease which has been known to wipe out entire crops. The creation of chickpeas that could be grown in summer decreased the riskiness of relying on the crop. In addition, the domesticated form of chickpea contains nearly twice the tryptophan of the wild form, an amino acid that has been connected with higher brain serotonin concentrations and higher birth rates and accelerated growth in humans and animals. See Kerem et al. for additional information. Genome Sequencing The first draft whole genome shotgun sequence of both desi and kabuli breeding lines was published in 2013. Varshney et al. discovered that genetic diversity was slightly higher in the desi, compared to kabuli, supporting earlier contentions that desi is the older of the two forms. The scholars identified 187 disease resistance genes homologies, considerably fewer than other legume species. They hope that others will be able to use the information collected to develop superior varieties with improved crop productivity and less susceptibility to disease. Archaeological Sites Domesticated chickpeas have been found at several early archaeological sites, including the Pre-Pottery Neolithic sites of Tell el-Kerkh (ca. 8,000 BC) and Djade (11,000-10,300 calendar years ago cal BP, or about 9,000 BC) in Syria, Cayà ¶nà ¼ (7250-6750 BC), Hacilar (ca 6700 BC), and Akarà §ay Tepe (7280-8700 BP) in Turkey; and Jericho (8350 BC to 7370 BC) in the West Bank. Sources Abbo S, Zezak I, Schwartz E, Lev-Yadun S, Kerem Z, and Gopher A. 2008. Wild lentil and chickpea harvest in Israel: bearing on the origins of Near Eastern farming. Journal of Archaeological Science 35(12):3172-3177. doi:10.1016/j.jas.2008.07.004 Dà ¶nmez E, and Belli O. 2007. Urartian plant cultivation at Yoncatepe (Van), eastern Turkey. Economic Botany 61(3):290-298. doi:10.1663/0013-0001(2007)61[290:upcayv]2.0.co;2 Kerem Z, Lev-Yadun S, Gopher A, Weinberg P, and Abbo S. 2007. Chickpea domestication in the Neolithic Levant through the nutritional perspective. Journal of Archaeological Science 34(8):1289-1293. doi:10.1016/j.jas.2006.10.025 Simon CJ, and Muehlbauer FJ. 1997. Construction of a Chickpea Linkage Map and Its Comparison With Maps of Pea and Lentil. Journal of Heredity 38:115-119. Singh KB. 1997. Chickpea (Cicer arietinum L.). Field Crops Research 53:161-170. Varshney RK, Song C, Saxena RK, Azam S, Yu S, Sharpe AG, Cannon S, Baek J, Rosen BD, Taran B et al. 2013. Draft genome sequence of chickpea (Cicer arietinum) provides a resource for trait improvement. Nature Biotechnology 31(3):240-246. Willcox G, Buxo R, and Herveux L. 2009. Late Pleistocene and early Holocene climate and the beginnings of cultivation in northern Syria. The Holocene 19(1):151-158.

Thursday, May 14, 2020

The Art and Science of Nursing - 670 Words

What do we know about nursing? To what extent do we understand nursing? How can we decide if we do â€Å"know† what nursing is? These are questions asked when we are developing knowledge about Nursing as both an Art and Science. Nursing gathers it generalized knowledge from experience with unique individuals from sources such as everyday non-scientific knowledge yet nursing always return to the individual for the application of its knowledge. What is nursing science? Nursing science is defined according to Barrett (2002) â€Å"as the substantive, discipline-specific knowledge that focuses on the human- universe-health process articulate in the nursing frameworks and theories† (p. 57). In general nursing science is the system of relationships and people response to health and illness addressing biological, behavioral, social, and cultural domains. There is still a debate ongoing as to if nursing is and occupation or a profession because nursing was viewed as an occupation not a profession. I think it is a profession because of the characteristics of the nursing profession which is (1) a body of knowledge, (2) code of ethics, (3) recognized authority by a profession group, (4) a professional organization that sets standards, (5) a strong service orientation, (6) autonomy, (7) ongoing research. It is also a profession that is always evolving in academic discipline and a science. According to Schlotfeldt, 1989, a prof ession must also have and institutionalized goal or social missionShow MoreRelatedIs Nursing an Art or Science1576 Words   |  7 Pages Is Nursing an Art or Science, or Both? NUR 1214 Abstract Nursing is defined and referred to as both an art and a science through theory and research in nursing practice. Although the science of nursing is grounded on the acquirement of knowledge and skills, along with theoretical understanding of nursing, but it is also described as ‘an experience lived between human beings’. Is Nursing an Art or Science, or Both? Introduction The terms science and art are essential for the nursing practiceRead MoreNursing as an Art and Science1150 Words   |  5 PagesTopic: The Art and Science of Nursing Name: Course: Instructor’s Name: Date: This paper seeks to explore Nursing practice in an attempt to demonstrate the change in perspective of the practice over the years from a traditional view to a more contemporary and realistic view. It will seek to achieve this by performing a literature review of two articles that not only talk but also define and distinguish nursing as both an art and a science and explore a nurses’ experience of being inRead MoreNursing As A Science And Art1439 Words   |  6 PagesQuestions to answer How nursing considered as a science and an art and discuss how the philosophy of nursing is applied to this definition. There is no contention that nursing is considered both as a science and art based on the dispensation of services to the community and patients. As a result of that, the paper seeks to explicitly elaborate the same by giving authentic distinction of why nursing is categorically classified on the two dynamics with a reflection of artistic and scientific intellectualismRead MoreArt And Science Of Nursing Essay2354 Words   |  10 PagesNursing practice is known as a combination of nursing knowledge and compassion in providing care and comfort to patients. Moreover, nursing practice has changed and developed into a dynamic profession to create a better health care environment. It is always essential to combine art and science aspects in nursing practice to help improve patients ‘outcomes. What is the art and science of nursing? Art and science of nursing is described in different ways through literature. According to Polos (2014)Read MoreArt And Science Of Nursing2238 Words   |  9 PagesArt and Science of Nursing For the 14th straight year, the public once again ranked nurses as most ethical and most trusted profession in the United States (Gallup, 2015). But what makes nurses the most ethical and most trusted profession? Is it the science of applying evidence-based practice? Is it the art of providing unwavering support and care to patients and their families? Or is it be both? The aim of this paper is to define the art and science of nursing, discuss its influences in currentRead MoreThe Art And Science Of Nursing1977 Words   |  8 PagesThe Art and Science of Nursing Nursing is a profession that has evolved greatly over time and encompasses many different roles. Initially, nurses were thought of as caregivers who followed the orders of physicians and had little autonomy. As the profession has grown, nurses now hold higher roles and increased responsibilities with regards to patient care. There are two sides to nursing, one includes the caring, compassionate, humanistic aspects and the other involves the skills-based, objectiveRead MoreThe Art And Science Of Professional Nursing Practice1173 Words   |  5 PagesThe Art and Science of Professional Nursing Practice Frequently, nurses are considered the foundation of the healthcare industry and the stakes are high when certain qualities must be possessed when working with patients and providing quality care. Nurses have a profound ability to apply strong skill-based knowledge with a caring and compassionate attitude that can improve patient outcomes. They also play an important role that can positively or negatively affect the way patients and family membersRead MoreDefinition And Concepts Of Art And Science Of Nursing2271 Words   |  10 Pagesconcepts of art and science of nursing, how each of these concepts affects nursing practice based on literature, relate how they influence my current personal practice, identify the influences on the changing health care environment, and examine how my nursing practice has changed in the last five years. I will also discuss the strategies I have used to apply the art and science of nursing in my practice and identify the approach I will utilize after c ompleting my Bachelor of Science in Nursing (BSN).Read MoreEssay about Nursing: A Profession of Art and Science1114 Words   |  5 PagesNursing is a dynamic profession built upon a foundation of art and science. It has adapted to rapidly changing technology, rising patient acuity, and weathered the challenge of nursing shortages with an unwavering commitment to professionalism. In this paper I will discuss my beliefs and values, my vision for the future, and my strengths and limitation in pursuing my career goals. I will also reflect upon the influences that contributed to choosing nursing as a profession. Choice of Nursing InRead MoreThe Theory Of Humanistic Nursing1458 Words   |  6 Pagesand effective nursing practice is a combination of art and science. Both the art and science of nursing are employed when working with a patient on their health goals. The art of healing is the communicative and relationship building skills while the science of nursing is the technical skills related to the field. Throughout nursing history, theories have been developed that attempt to explain the role of the nurse. These theories often try to either explain the science or art of nursing. Some of these

Wednesday, May 6, 2020

Fashion Retail Management - 3781 Words

RETAIL OPERATIONS Course Material for Master of Fashion Management Students. RETAIL OPERATIONS Definition of Retail Operations Retail Operations professionals manage retail establishments on a daily basis, and are responsible for maximizing store profits. The National Retail Federation (NRF) reports that retail operators may also manage human resources and loss prevention. The retail store is of prime importance to the retail origination, for two reasons. †¢ The retail store is the primary source of revenue for the retailer and †¢ It is the point where the customer actually interacts with the retail store and its Offerings. The primary responsibility within the environment of a retail store lies with the store manager. The†¦show more content†¦Ã¢â‚¬ ¢ Improve resource allocation through analysis of performance data. †¢ Identify problem areas quickly by monitoring key performance indicators . †¢ Get real-time visibility into management and performance of the organization. †¢ Improve sales and marketing by consolidating customer, channel and product data for a single view of revenues and market share. †¢ Monitor performance at national, regional, territory and product levels using dashboards and scorecards. †¢ Improve manufacturing process and inventory control management †¢ Forecasting |RETAIL OPERATIONS KEY PERFORMANCE INDICATORS(KPI) | | |Customer Service | | |Profit Loss | | |People | | |Product Performance |Show MoreRelatedFashion Retail Management2185 Words   |  9 PagesFashion Retail Management Submitted to, Mr. Sushil Raturi Submitted by, Akansha Choudhary M/FMS/08/03 Ashish Singh M/FMS/08/08 Kanika Srivastava M/FMS/08/13 Pooja Jaiswal M/FMS/08/18 Rajat Abrol M/FMS/08/23 Sevesh Ranjan M/FMS/08/28 Watan Gupta M/FMS/08/35 National Institute of Fashion Technology Page 1 Fashion Retail Management OBJECTIVE To analyze a fashion brand and study it from the following aspects:- ï€ ¿ ï€ ¿ ï€ ¿ ï€ ¿ ï€ ¿ ï€ ¿ POSITIONING TARGET CUSTOMER PRODUCT MIX PRICING DISTRIBUTIONRead MoreResearch on Fashion Retail Management2100 Words   |  9 Pages.............................................09 * STORE LOCATION†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦14 * STORE OPERATIONS†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦....15 * STOREFORMATS†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.................†¦..18 * CONCLUSION†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.................†¦Ã¢â‚¬ ¦19 Introduction Retail  consists of the  sale  of physical goods or merchandise from a fixed location, such as a  department store,  boutique  or  kiosk, or by  mail, in small or individual lots for direct consumption  by the purchaser. Retailing may include subordinated servicesRead MoreFactors Influencing International Fashion Retailers816 Words   |  4 Pages Paper Critique: Factors influencing international fashion retailers entry mode choice. Lu, Y., Karpova, E. and Fiore, A. (2011) Factors influencing international fashion retailers entry mode choice, Journal of Fashion Marketing and Management: An International Journal, 15(1), pp. 58-75. doi: 10.1108/13612021111112340. Summary: The aim of the paper is to provide a theory†based framework that informs a fashion retailer s entry mode choice into a foreign market. The author highlights theRead MoreCase study: ASOS and Topshop1547 Words   |  7 Pages10 1.0 Introduction ‘Fashion industry is characterised by short product life cycles, volatile and unpredictable demand, tremendous product variety, long and inflexible supply processes and a complex supply chain.’ (Sen, 2007, pp. 1) Due to the nature of the fashion industry, the demand in supply chain changes rapidly. Time is a crucial factor for fashion and therefore supply chain management should be sensitive according to the change in demand (SullRead MoreHuman Resource Strategies Of Fashion1663 Words   |  7 PagesAustralia’s fashion industry thrived. Later on the 20’s the industry has grown across suburbs, designer as well as brands has spread across Australia. However, Australian fashion retailer is in a challenging position, it has become a global shift in the last few years, with 15 percent of the world’s top 250 retailers has already set up stores in Australia (Heffernan, 2015). In this essay an attempt will be made to discuss the statement mentioned above and its implications on David Jones fashion retail businessRead MoreThe Future Of Fashion Retailing1635 Words   |  7 PagesThe future of fashion retailing is working competitively to bring what loyal customers want in stores. Not all fashion companies grow a company in the United States, but rather in different countries, such as Japan, Spain, and Sweden. From the Forbes magazine, writer Greg Petro discusses how three fashion companies, Uniqlo, Zara, and HM, have expanded globally outside of their home country into the United States. Petro wrote an article back in 2012 about these three well-known fashion companies. RecentlyRead MoreSop for Design Management1004 Words   |  5 Pagesthe high school, I accidentally came across a book about branding and retail management that triggered my vague interest in marketing communication and management. In retrospect, it was precisely this vague notion that developed into a strong desire, an unshakable ideal that I am determined to pursue with lifelong dedication. But when I succeeded in my National Institute of Fashion Technology, exam, I started loving art and fashion, and creativity and imagination became natural extensions of my enthusiasmRead MorePantaloons Case Study1544 Words   |  7 PagesCase Study2: Pantaloons Retail India Limited Abstract: This case talks about Pantaloons Retail India Limited, a growing company in the still nascent apparel retail sector in India. The case has brief description of the Indian Retail industry and the changes happening in the industry with the development of smaller cities and towns and also about the customers changing behavior. The case then discusses about how Pantaloons have are capturing this market and the evolution of the Pantaloons store brandsRead MoreManagement and Zara1507 Words   |  7 Pagescurrently Spains richest man. Zara specializes in fast fashion. At the end of fiscal year 2001 Zara was operating 1,284 stores world wide and had total revenue of €3,250 million. Inditexs headquarters and its major assets are located in the Galacia region of Spain. Inditex also operates five other chains: Massimo Dutti, Pull and Bear, Bershka, Stradivarius and Oysho. Zara owns both its production and retail units which give the upper management a better overall control. They have successfully integratedRead MoreZara Case Study1656 Words   |  7 Pagesfor the Spanish Inditex Group owned by Amancio Ortega, who also brands such as Massimo Dutti and Bershka. It was first open in 1975 in La Coruna, Galicia, Spain. Originally a lingerie store, then the product range expanded to incorporate women’s fashion, menswear and children’s clothes (5). The international adventure began in 1988, opened its first foreign store in Oporto, Portugal. The market growth remained mysterious and it kept growing the stores in different countries and its cities. Started

Tuesday, May 5, 2020

Web Design free essay sample

Web design it has different meanings in different fields, it’s the creation of a plan for the convention of an object. It can be used in areas like architectural, engineering, business, circuit diagrams and patterns of sewing. Web design is a similar process of creation, which the end-users can access the internet with the help of a browser. It had elements like; layout, color, graphics, fonts and content. Besides the essential elements that make a web design beautiful and visually compelling a website must also consider its users, and it should be user-friendly.Web design has different skills and disciplines in the production and maintenance of websites. These areas include graphic web design, interface design such as authoring, including standardized code and proprietary software, user experience design; and search engine optimization. Many times, web design experts will work in different scopes covering different aspects of the design process, although some designers will include them all. We will write a custom essay sample on Web Design or any similar topic specifically for you Do Not WasteYour Time HIRE WRITER Only 13.90 / page Web design partially overlaps web engineering in the broader range of web development. Those who design the web are expected to have an awareness of usability, and if their role involves creating mark up, then they are also likely to be up to date with web accessibility guidelines.Web designers use a range of tools depending on what part of the process of production involving them. This paraphernalia often updated by newer software and standards, though the rules remain the same. Web designers use both raster graphics editor and vectors to create web-formatted imagery or design prototypes. Technologies used to develop websites include W3C standards like CSS and HTML, which can be hand-coded or generated by WYSIWYG editing software. Other tools web designers might use include markup validators and other testing tools for usability and accessibility to ensure their websites meet web accessibility guidelines. ConclusionThough it is a tight field, Web design is a vital knowledge which should be learned be owners of businesses. It can increasingly help them design websites which increasing market coverage and profits

Sunday, April 5, 2020

Cancer Essays (683 words) - Apoptosis, Programmed Cell Death

Cancer Good morning ladies and gentlemen, my colleagues and I have called you in at such short notice because we need to discuss a patient who was brought to our attention earlier this week. The patient presented with rapidly progressing lymphadenopathy, subsequent examination lymph nodes congested with many small B-lymphocytes. The B-lymphocytes showed a significant chromosomal aberration in the form a 14;18 translocation. The patient has been diagnosed with lymphoma and has been prescribed an immediate course of chemotherapy. This morning's presentation will include a short description of the cell cycle and how and where certain checkpoints of genomic integrity function. My colleagues Associate Professor Cath and Dr Lucia will then explain the steps involved in contracting lymphoma with regards to the chromosomal translocation and its implications. The cell cycle is broken functionally into 4 sections, Growth 1, Interphase, Growth 2 and the Mitotic Phase. During Interphase the cell goes about replicating DNA in preparation for Mitosis. During the Growth 2 phase the cell synthesizes the proteins and enzymes required to perform the mitotic division, as well as transporting these enzymes to their appropriate positions within the cell. The Mitotic phase is where the cell undergoes division into two separate daughter cells. The Growth 1 phase is the phase we are most concerned with; it is characterised by rapid growth and metabolic activity and a high rate of protein synthesis. It is also the phase where oncogenic processes have their most profound effect. Late in the growth 1 is considered a point of no return within the cell cycle, because once the cell has past into Interphase, it will usually complete a successful cell division. In order to protect the integrity of the cellular genome a number of checkpoints are present which can halt the cell cycle, and if necessary, induce apoptosis. Apoptosis, or programmed cell suicide, involves the synthesis of enzymes like BAX, which bring about the death of the cell within a matter of minutes. Apoptosis is induced either when a cell is no longer required, for example extra lymphocytes formed to fight an infection once that infection has been overcome, or when irreparable damage has been detected in the genome. To ensure there isn't random cell suicide, so-called survival genes such as BCL-2 prevent apoptosis unless a specific series of events takes place. However as you can imagine, overproduction of such a gene produces a cell of exceptional fortitude, which can make for a considerable danger if combined with certain genetic errors, as we will hear from (CATH OR LUCIA) Perhaps the most important checkpoint is the p53 protein. The gene encoding the p53 protein is the most common mutation in all human cancers. In response to genomic damage p53 binds to DNA and exerts it's influence by inducing the transcription of another regulatory gene whose product binds to certain complexes required to drive the cell past the Growth 1 phase. Blocking the activity of these complexes prevents entry into interphase and therefore DNA replication. This allows time for the damage to be repaired by enzymes which may also be induced by p53. While the precise mechanism with which p53 is alerted to the aberration remains uncertain, some aspects of the pathway are becoming clear. The Ataxia-telangiectasia mutated gene or ATM plays a role in activating p53 in response to low-level, repairable DNA damage. It is thought that (see diagram in Enoch and Norbury) cells respond to high and low levels of DNA damage differently. ie at low levels P53 is activated transiently via a dir ect sensor in ATM to repair the minor damage, once the repair is complete P53 goes away and the cell progresses into Interphase. If there is major DNA damage, P53 is continuously induced (in the absence of ATM) and promotes apoptosis by either directly activating death genes like BAX or by down-regulating survival genes like BCL-2. Errors in these checkpoints often lead to conditions like the lymphoma presented in the patient in question. Dr Lucia/Cath will provide an insight into what happens when things go wrong. Science

Sunday, March 8, 2020

Free Essays on The Plantation Mistress

â€Å"The Plantation Mistress† By Catherine Clinton The Plantation Mistress focuses on the elite women living on plantations with twenty or more slaves in the seven seaboard states of the plantation South during the period between 1780 and 1835. Through the study of nearly 500 manuscript collections that housed the contents of family letters, household inventories, the papers of female academies, commonplace books and physicians’ records Clinton attempts to shed light upon the hidden lives of southern plantation mistresses, who she states, have been prisoners of myth, legend, and folklore. Many of the diaries and memoirs she studied are unpublished and unexamined. Clinton reveals the life of a plantation mistress and her role as wife, mother, and household manager in the antebellum South. Additional areas of discussion include kinship, courtship, marriage, and divorce; moral standards; health and childbearing; the isolation of plantation life; the â€Å"curse of slavery† and the â€Å"sexual dynamics of slavery.† Clinton believed that southern women occupied an undesirable position with respect to women of the North. She found that southern women married at a younger age, had more children, and died earlier, often in childbirth. They were also burdened with more complex tasks of household management and lived in greater isolation; thus reducing the female companionship of emotional support and social gatherings. Far from the life of leisure, women were really prisoners of the southern male system. Clinton states that slavery contributed to the oppression of women: â€Å"Patriarchy was the bedrock upon which the slave society was founded, and slavery exaggerated the pattern of subjugation that patriarchy had established† (p. 6) It was an oppression that equaled and in some ways exceeded that experienced by slaves. â€Å"These women were merely prisoners in disguise† (p. 109) Overall, women in the antebellum South were gen... Free Essays on The Plantation Mistress Free Essays on The Plantation Mistress â€Å"The Plantation Mistress† By Catherine Clinton The Plantation Mistress focuses on the elite women living on plantations with twenty or more slaves in the seven seaboard states of the plantation South during the period between 1780 and 1835. Through the study of nearly 500 manuscript collections that housed the contents of family letters, household inventories, the papers of female academies, commonplace books and physicians’ records Clinton attempts to shed light upon the hidden lives of southern plantation mistresses, who she states, have been prisoners of myth, legend, and folklore. Many of the diaries and memoirs she studied are unpublished and unexamined. Clinton reveals the life of a plantation mistress and her role as wife, mother, and household manager in the antebellum South. Additional areas of discussion include kinship, courtship, marriage, and divorce; moral standards; health and childbearing; the isolation of plantation life; the â€Å"curse of slavery† and the â€Å"sexual dynamics of slavery.† Clinton believed that southern women occupied an undesirable position with respect to women of the North. She found that southern women married at a younger age, had more children, and died earlier, often in childbirth. They were also burdened with more complex tasks of household management and lived in greater isolation; thus reducing the female companionship of emotional support and social gatherings. Far from the life of leisure, women were really prisoners of the southern male system. Clinton states that slavery contributed to the oppression of women: â€Å"Patriarchy was the bedrock upon which the slave society was founded, and slavery exaggerated the pattern of subjugation that patriarchy had established† (p. 6) It was an oppression that equaled and in some ways exceeded that experienced by slaves. â€Å"These women were merely prisoners in disguise† (p. 109) Overall, women in the antebellum South were gen...

Friday, February 21, 2020

Final Reflection Paper Essay Example | Topics and Well Written Essays - 250 words

Final Reflection Paper - Essay Example These tools and methods when effectively and correctly applied, the goal is achieved and this can be obtained by also working with an expert researcher in the field. I have discovered through this study that the central theme in every research is in discovering the problem. This is the first approach in any research that calls for concise analysis of the problem described in a clear and precise term that is easy to understand (Leedy & Ormrod, 2013).Once this is done, the researcher can view literature that is related with the subject of study thoroughly and efficiently in order to gather enough information that would lead in the planning of research design. The research process, therefore, takes a course in which a researcher communicates his thoughts, objectives, plans, and methods in a manner that others can read (Leedy & Ormrod, 2013). Through this approach, it is imperative that any research collect adequate information and examine them keenly with a motive of constructing a rich and meaningful picture of a situation. In conclusion, the essence of research is not in merely collecting information but in arriving at a solution to the problem. Having garnered this wealth of information, it is easier for me to correctly undertake a research and achieve

Wednesday, February 5, 2020

Marketing Case Research Paper Example | Topics and Well Written Essays - 2250 words

Marketing Case - Research Paper Example Primary aim of marketing is to understand, attract, communicate, and to maintain relationship with the target audience and hence, marketing is useful for the task where target consumers are important. This paper will attempt to frame a set of plausible marketing strategy for Canadian Museum for Human Rights (CMHR) for attracting large of visitors including domestic and foreigners. This is the national museum of Canada to be established by the Canadian Government. Currently, this museum is under construction, and the task for establishment was started from August 10, 2008 after the Parliamentary amendments of Museum Act on March 13, 2008. It is supposed to open from 2012 and will aim to offer the world a platform for engaging in discussions about serious issues like hate, oppression and suppression (Canadian Museum for Human Rights-a, 2010). The marketing activity for CMHR is communicating with the target audience for promoting its value and for understanding of human rights. This wil l help it to meet the commitments of Canadian Government to support â€Å"democracy, freedom, human rights, and the rule of law† (Canadian Museum for Human Rights-b, 2010). SWOT Analysis Strengths The biggest strength of the museum lies in its location based advantages. Canada being one of the developed nations, adds to the popularity of the museum. It also helps in garnering funds as the government has provided full support for the museum. Another major strength of the organization is the unique concept by which the museum has been conceptualized. The noble and unique nature of the museum helps in increasing the awareness of the individual’s on the aspect of human rights (Canadian Museum for Human Rights-a, 2010). The uniqueness of the museum also lies in its innovative, interactive and high technology environment that would enable interactions such as debates with regard to human rights. Any person can submit his/her story about human rights violations and the museum would provide a platform for sharing it across the globe (Krell, 2009, p.50). Weakness Lack of awareness about the concept of the museum amongst the target audience seems to be the most formidable weakness of the museum. This lack of awareness leads to generation of considerable weakness as people may not be aware of the museum. This would hamper the very basic intention of setting up the museum. Opportunities Being located in a developed nation and set up with a noble and unique concept generates large scale opportunity for the museum to draw visitors. The museum also provides opportunity for individuals to highlight their stories about human rights violations to showcase their problems on a global platform. Human rights violations form one of the most burning issues and there have been numerous issues of human rights violations which remain unreported due to lack of a proper platform. The museum with its unique concept would help in generating large scale opportunities that would help in drawing large crowds and make it a success story. Threats There have been certain controversies regarding the site of the project as many claim it as a land that has historical significance and building a structure over it

Tuesday, January 28, 2020

Melkersson-Rosenthal Syndrome: A Case Study

Melkersson-Rosenthal Syndrome: A Case Study Dr. Shruti Bohra Dr Pratik B Kariya Dr Seema Bargale Abstract: Melkersson-Rosenthal syndrome (MRS) classically shows a triad of orofacial swelling, fissured tongue and facial palsy, more commonly the oligosymptomatic form. The orofacial swelling is characterized by fissured, reddish-brown, swollen, nonpruritic lips or firm edema of the face. The facial palsy is indistinguishable from Bells palsy. The least common feature is fissured tongue, although seen in one third to one half of patients but when present it assists in the diagnosis. The histologic finding of MRS includes noncaseating, sarcoidal granulomas, not invariably but their absence does not exclude the diagnosis. All these findings together provoke the careful search for provocative causes for the reactive symptom complex of the Melkersson-Rosenthal syndrome. Key words: Melkersson-Rosenthal syndrome. chelitis granulomatosa, facial palsy, fissured tongue. Introduction: Melkersson-Rosenthal syndrome is considered to be a rare syndrome. Hornstein- estimated the incidence to be 0.08%.1MRS is a non-caseating granulomatous disease showing (complete or incomplete form) a triad of facial paralysis, orofacial oedema and fissured tongue (scrotal tongue, lingua plicata, or furrowed tongue). Orofacial swelling is the most consistent and dominant feature of the Melkersson-Rosenthal syndrome. In a review of 200 patients diagnosed with Melkersson-Rosenthal syndrome, it was the most frequent initial presenting sign.2Most commonly the lips are affected, with the swelling sometimes confined only to the lips. Cheilitis granulomatosa (or granulomatous cheilitis) is achronic inflammatory granulomatous swelling of the lip, which is referred as Miescher cheilitis which is generally regarded as a monosymptomatic form of the Melkersson-Rosenthal syndrome.3 Melkersson-Rosenthal syndrome usually presents in a monosymptomatic or oligosymptomatic form. Around 200 cases are re ported in a review of Zimmer et al2, we hereby report an additional case. Case report: A 16 year old female patient reported to dental OPD with the chief complaint of generalized gingival enlargement as well as swelling in upper and lower lip since 8-9 months. Patient was apparently alright 9 months back when she had an episode of fever which lasted for 8 days and subsided with medication taken from a local clinician. It was followed by episodes of remission exacerbation of gingival enlargement with swelling of upper lip with pus discharge and bleeding to touch since 8-9 months. Then patient was referred to the department of oral pathology for needful. On examination face was bilaterally asymetrical with swelling of face on right side. Both upper and lower lips were swollen (markedly swollen upper lip) (Fig: 1). On palpation the swelling had normal temperature, was not painful, and was nonpitting and rubbery in consistency. Face was flattened on left side. Mandible was deviating on right side on opening of mouth. On intraoral examination generalized gingival enlargement was noticed which was covering cervical 1/3rd of almost all the teeth present in the oral cavity (Fig: 2). Teeth preset were incisors to second molars in all four quadrants. The tongue had deep grooves and fissures. A long prominent central groove was evident on the dorsum of the tongue going in a straight line with numerous small grooves and fissures running laterally from the middle third of the tongue (Fig: 3). An initial diagnosis of angioedema was made. Diphenhydramine hydrochloride, 100 mg, was administered intramuscularly followed by a course of diphenhydramine hydrochloride, 50 mg orally, four times a day. After 24 hours no noticeable reduction in facial swelling was evident. Therefore, re-evaluation of the diagnosis was necessary. As a result of this history, recurrent cheilitis granulomatosa consistent with Melkersson-Rosenthal syndrome (MRS) was added to the differential diagnosis. A biopsy specimen of the affected lip area was sent for histopathologic examination, confirming the final diagnosis of MRS. On histopathological examination the mucosa consisted of parakeratinized, hyperplastic, stratified squamous epithelium overlying collagenous connective tissue. Within the connective tissue there were discrete aggregations of lymphocytes, generally with a perivascular distribution; however, some bad central foci of histiocytes consistent with granulomatous lesions. The histologic findings were consistent with cheilitis granulomatosa. (Fig: 4) Treatment consisted of application of lip gloss to prevent cracking of the exposed mucosa. No further treatment was deemed necessary except continuation of his regular biannual preventive recall appointments. Discussion: Melkersson-Rosenthal syndrome (MRS) classically shows a triad of orofacial swelling, fissured tongue and facial palsy. Oligosymptomatic form of this syndrome is more common one of the example is Miescher cheilitis.3Melkersson-Rosenthal syndrome may often go undiagnosed for some day as in present case. History states that Rossolino in 1901 was the first to describe a particular association of oedema of the face, facial nerve palsy and scrotal tongue, the syndrome was named after Melkersson and Rosenthal.4 In 1928, Ernst Melkersson, a Swedish physician, described a 35-year-old woman with facial edema and paralysis. Shortly after, in 1931, Curt Rosenthal, a German neurologist, described 3 patients who had fissured or plicated tongues in addition to orofacial swelling and facial palsies and proposed a link between the triad of symptoms. Subsequently, the triad of clinical findings came to be known as the Melkersson-Rosenthal syndrome. Although MRS is reported as commonly found during the second to fourth decades of life, there are many published reports of MRS in children and preadolescents, Roseman et al 7 described a case of MRS in a 7-year-old girl, Cohen et al 8 described four cases of MRS in children younger than the age of 11 years, and Yuzuk et al 9 described the case of a 13-year-old girl who presented with the oligosymptomatic form orlabial edema coupled with fissured tongue. Melkersson Rosenthal syndrome does not appear to have an obvious predilection for either sex, although Some claim that it is slightly more common in females. 6,7,8 No particular racial predilection has been noted in MRS. Etiology of this disease remains largely unknown. 10 In granulomatous cheilitis normal lip architecture is altered by presence oflymphoedemaand noncaseating granulomas in the lamina propria.TH1 immunocytes produceinterleukin12 and RANTES/MIP-1alpha and granulomas.Expressionof protease-activatedreceptor1 and 2 occurs in orofacial granulomatosis (OFG).HLA typingmay show HLA-A2 or HLA-A11.11 Pathogenesis of MRS was suggested by Hornstien.1 He suggested that abnormal regulation of the autonomic nervous system leads to excessive permeability of the facial cutaneous vessels. From this abnormal circulation, nonspecific antigens then stimulate the perivascular cells to form granulomas. Obstruction of perivascular vessels by granuloma has been proposed as a causative factor in the swelling. 1 Initially, a patient with MRS usually complains of painless facial swelling that has persisted for a long time. Further investigation may reveal a history of previous episodes of swelling associated with facial paralysis or fissured tongue that the patient has never connected. The most common symptom of MRS is recurring orofacial swelling in which the upper lip is more often affected. Other areas affected by orofacial swelling in MRS in order of frequency, are cheek, nose, eyelid, alveolar process, and chin.2,12 Zimmer et al 2 reported orofacial manifestations in 42 patients with MRS who were examined at their clinic: they also reviewed 220 cases reported in the literature between 1965 and 1990. They found that 82% of patients presented with labial swelling, 40% had swelling in other parts of the face, not including the lip, 24% had Bells palsy, and 59% had fissured tongue. Other areas of intraoral swelling were, in order of frequency, the gingiva ( 11 % ), buccal mucosa ( 16% ) palate (8%). and tongue (7%). The swelling of the face and lip is described as recurrent, nontender, nonpitting, and firm, but not of hard consistency. The orofacial swelling is usually sudden and, in most cases, precedes facial paralysis by weeks, months, and even years. 2, 5, 6. First episodeof edema sometimes accompanied by fever and mild constitutional symptoms (as seen in present case e.g. headache, visual disturbance) usually subsides completely in hours or days. Recurrences can range from days to years, each recurrent episode lasts longer and is more pronounced, and swelling may ultimately become permanent. 2,5,6 The facial paralysis associated with MRS is frequently indistinguishable from Bells palsy. The site affected by paralysis usually corresponds to the site of swelling. As in the present case with facial swelling, the paralysis is on right side. Each recurring episode is more profound and lasts longer. 6,13,14 Other neurologic presentations associated with MRS are altered taste, migraine headaches, and trigeminal neuralgia.2,5,6,13,15 Fissured tongue ( eg. lingual plicata) is usually found at birth and therefore considered an incidental finding of MRS. Nevertheless, fissured tongue is ten times more likely to be found among individuals diagnosed with MRS than in the general population. 2, 6, 15. Miyashita et al 16 described MRS in a 56-year-old woman, who was afflicted with cheilitis granulomatosa caused by lingual candidiasis of a fissured tongue. The edematous lesion, on histopathologic investigation, is a noncaseating epithelial cell granuloma with perivascular mononucleated lymphocytic infiltrate. Fibrosis of the granulomas is typical in long-term and recurrent lesions. 1,2,17 Differential diagnosis includes Crohn’s disease, sarcoidosis, Aschers syndrome, and allergic angioedema, leprosy, tuberculosis.1,5,15,17,18,19 In Lab studies Serum angiotensin-converting enzymetestmay be performed to help exclude sarcoidosis.Reactions to metals, food additives, or other oral antigens are excluded by using Patch tests which may be associated with some cases of granulomatous. 20 If found positive they are advised to avoid the allergen. Imaging studies like gastrointestinaltractendoscopy, radiography, and biopsy may be used to differentiate from Crohn disease. Chest radiography or gallium orpositron emission tomography(PET) scanning may be found helpful in excluding sarcoidosis and tuberculosis. Orthopentamogram (OPG) helps in ruling out presence of a chronic dental abscess. A final diagnosis of MRS is made from the clinical history and histopathologic assessment of the edematous tissue, which usually includes the lip. When biopsy of the edematous tissue is difficult or not warranted, then a history of recurrent idiopathic facial swelling associated with atleast one of the following two entities, idiopathic facial paralysis (ie. Bells palsy) or fissured tongue, is sufficient to make a positive diagnosis of MRS. Treatment of MRS is aimed at the facial swelling and the paralysis. Because the etiology and pathogenesis of MRS are not well understood, treatment continues to be empirical and, in most cases, unsuccessful. Fortunately, both the swelling and the paralysis are selflimiting and usually go into remission on their own. Treatment with oral prednisone or nerve decompression has been shown to be effective.1,5,6 Treatment with oral prednisone or nerve decompression has been shown to be effective.5 Also, interlesional injections with triamcinolone hexacetonide suspension have been shown to provide temporary benefit.12 Plastic surgery may be considered in the case of permanent fibrotic lesions. Nevertheless, thorough documentation by many dentists eventually allowed MRS to be included in the differential diagnosis. This case highlights the importance of good history taking, regular follow-up and thorough documentation for proper patient management. References: HornsteinOP. Melkersson-Rosenthul syndrome: A neuromucocutaneus disease of complex origin. Curr ProbI Dermatoi 1973 ;5:117-156. Zimmer WM, Rogers RS. Reeve CM, Sheridan PJ. Orofacial manifestations of MeIkersson-Rosenthal syndiume: A study uf 41patients and review of 22tn cases from the literature. Oral Surg Oral Med Oral PiU ho I IW:;74:61O-6I9. Rogers RS 3rd: Melkersson-Rosenthal syndrome and orofacial granulomatosis, Dermatol Clin.1996 Apr;14(2):371-9 Magid El Shennawy and Galala El Enany: Melkersson-Rosenthalsyndrome; Review of theliteratureand report of acase, The Journal of Laryngology Otology Volume87 / Issue09 /September 1973, pp 898-902 Green RM. Rogers RS, Melkersson-Rosentlial syndrome: A review of 36 patients. J Am Acad Dermatoi 1989:21:1263-1270. Orlando MR, Atkjns JS Jr. Melkersaon-Rosenthal syndrome. Arch Otolaryngol Mead Neck Surg I99O;116:728-729. Roseman B, Fryns JP, Van den Bergle C Melkersson-Rosenthal syndrome in a 7-year-old girl. Pediatrics 197S;61:490-491. Cohen HA. Cohen Z, Ashkenasi A, Straussberg R. Frydman M, Kauschansky A, Varsano 1. Melkersson-Rosen thai syndrome. Cutis 1994:54:327-32S. Yuzuk S, Trau H, Levy A. Shewaeh-Millet M. Melkersson- Rosenthal syndrome. Int J Dermatoi i9SS:24;456-457. Tilakaratne WM, Freysdottir J, Fortune F. Orofacial granulomatosis: review on aetiology and pathogenesis.J Oral Pathol Med. Apr 2008;37(4):191-5. Ketabchi S, Massi D, Ficarra G, et al. Expression of protease -activated receptor-1 and -2 in orofacial granulomatosis.Oral Dis. Jul 2007;13(4):419-25. Miele FA Jr. Tlie big lip. Diagnostic and treatment considerations. Gen Dent 1994;42O.i8-:59. Graff-Badlord SB. Melkersson-Rosen thai syndrome, A review of the literature and a case report. South Afr Med J 1981:60:71-74, Balatiieh AB. Pillai KG, Maiisour M. Ai-Khail AA. An unusual case of the Melkersson-Rosenthal syndrome. Oral Surg Oral Med Oral Pathol 1995:80:289-292. Winnie R, DeLuke DM. Mel kersson-Rosenthal syndrome: Review of literature and case report. Int J Oral Ma.illofac Surg 199;;; 1:115-117 Miyashita M, Baba S, Suzuki H. Role recurrent oral caniiidiasis associated with lingua plicata in Me I kersson-Rosen thai syndrome. BrJ Dermatol 199Ã ®:l.l2:.ll 1-312. Minor MW Fo^ RW, Bukant; SC, Lockey RF. Melkersson- Rosenthal sjndrome. J .Miergy Clin Immunol l9a7;S0:64-67. Kano Y, Shiohara T. Yagita A, Nagashima M. Association between cheilitis granulomatosa and Crohns disease. J Am Acad Dermatol 1993:281:801. Lloyd DA, Payton KB, Guenter L, Frydman W. Melliersson-Rosenlhal syndrome and Crohns disease: One disease or two? Report of a case and discussion ofthe literature. J Clin Gastroenterol I994;18:213-2I8. Fitzpatrick L, Healy CM, McCartan BE, Flint SR, McCreary CE, Rogers S. Patch testing for food-associated allergies in orofacial granulomatosis.J Oral Pathol Med. Jan 2011;40(1):10-3. Figure legends: Figure no 1) extraoral photograph showing swollen upper and lower lips. Figure no 2) intraoral photograph showing generalized gingival enlargement Figure no 3) intraoral photograph showing deep grooves on dorsal surface of tongue Figure no 4) photograph showing histological presentation of chilitis glanduralis at low power (10X) and high power (40X) Learning ponts Concomitant presence of orofacial swelling, fissured tongue and facial palsy or any one of them may be a case of Melkersson-Rosenthal syndrome (MRS). A final diagnosis of MRS is made from the clinical history and histopathologic assessment of the edematous tissue. Melkersson–Rosenthal syndrome may recur intermittently and can become a chronic disorder. Gold: History, Properties and Nanoscale Analysis Gold: History, Properties and Nanoscale Analysis Since first extracted in the 5th century, Gold has been regarded as one of the most important matters in the world. When divided into smaller fragment sizes, way below 100nm it becomes even more ‘precious’. The optical, catalytical and electronic properties of Gold nanoparticles differ greatly from those of their bulk counterparts. This is mainly due to the large surface area-to-volume ratio as well as the spatial confinement of the free electrons of Gold nanocyrstals. Gold at Bulk scale Noble metals such as Gold, silver and platinum exhibit plasmonic properties. When the surface of a noble metal is hit with incident light, electrons which are situated on the surface begin to oscillate. This is known as the surface plasmonic resonance (SPR), as illustrated in figured 1. Metals are able to absorb and reflect light with great efficiency to their SPR. It is because of these plasmonic properties that noble metals such as Gold, silver and platinum are widely used in jewellery. Moreover being highly reflective metals makes them very appealing to the eye. Plasmonic properties arise due to noble metals having delocalised electrons on the surface. An atom consists of protons, electrons and neutrons. The nucleus is made up of protons and neutrons and the electrons spin around the nucleus in different orbitals. There are many orbitals in metals which overlap and form metallic bonding between the atoms. In the bulk form, there are many delocalised electrons within the metal that cause metallic bonding. This in turn allows the electrons to flow freely between the nuclei. Good electrical and thermal conductivity is due to the delocalised electrons Gold at Nanoscale Reflection does not occur in particles which are smaller than the wavelength of the incident light; however there is still an interaction between the nanoparticles and the light. The two main interactions are light scattering and light absorption. Electrons tend to oscillate at the same frequency as the light which was absorbed causing a dipole moment around the nanoparticles where all the electrons on the surface of the nanoparticle are oscillating. The oscillating dipole is known as a localised surface plasmon resonance (LSPR). Electromagnetic radiation is released when these electrons are oscillated. This can be seen in figure 2. The secondary electromagnetic radiation released by the nanoparticles is called scattered light. The electromagnetic radiation that is released has the same frequency History The synthesis of colloidal gold, or nanogold as it is now called, has been known to man since the ancient times. Although the process was not fully understood, synthesis of colloidal gold was crucial to the 4th century Lycurgus cup. The Lycurgus cup was known to change colour depending on the direction of light. Later it was used as a method for staining glass. A potion made from gold, which was also known as an Elixir of Life was discussed, and may also have been manufactured, in ancient times. It was not until the 16th century that the alchemist Paracelsus, claimed that he had created a potion called Aurum Potabile. (latin: potable gold). It was in the 17th century that the glass-colouring process was refined byAndreus CassiusandJohann Kunckel, allowing them to produce a deep-ruby coloured form of glass. However modern scientific evaluation was first made by Michael Faraday in the 1850s. Faraday is said to have been inspired by previous work done by Paracelsus. In 1857 Faraday prepared the first pure sample of colloidal gold, which he called activated gold, in 1857. Phosphorus was used to reduce a solution of Gold chloride. For a very long time chemists were unclear about the composition of the Cassius ruby-gold. Several chemists suspected Cassius ruby-gold to be a gold tin compound due to its preparation, However it was Faraday who was the first to recognize that the colour was actually due to the minute size of the gold particles The first colloidal gold in solution was first prepared in 1898 by Richard A. Zsigmondy. Shape and size tuning Fine tuning of shape and size in a controlled environment is one of greatest challenges faced by material scientists. These factors are not only very important in the rational design of nanomaterials, but are also equally as important for their applications. This is because many of their catalytical, optical and electronic properties of nanomaterials depend greatly on their size and shape. In Gold nanorods the longitudinal plasmon wavelength exhibits a nearly linear dependence on their aspect ratio, making it one of the most intriguing properties possessed by Gold nanorods. Moreover, even when looking at Gold nanorods with the same aspect ratio, the plasmon resonance properties are strongly dependent on the shape of their head. Over the past five years, the ability to finely tune the shape and size of Gold nanorods, has made huge progress. Seed mediated growth Gold nanospheres Changing the diameter of the sphere can easily and effectively tune the optical properties of gold nanospheres. This can easily be shown using the Mie Theory, which has been successfully shown to model the light scattering and absorption properties of spherical particles on a nanometer scale. The intense peak in the spectrum for each particle can be seen in figure 9. This peak is caused by the oscillating electrons which in turn produce a single dipole. Increasing the diameter of the gold nanosphere results in shifting the peak to a higher wavelength, this indicates the interaction between the light and particles is changing. In comparison to bulk gold (figure 4), the optical properties of gold nanospheres differ immensely. The local medium can also change the optical properties of the particles. This is due to the LSPR of the particle interacting with the medium. A change in the medium can result in a measurable change in the optical properties of the particles. In addition shape of the gold nanoparticles can significantly alter the optical properties. Gold nanorods Gold nanorods are of great interest due to their biocompatibility and NIR ( near infra-red) optical properties. The shape of the gold nanorod is what determines its NIR properties. The non-spherical shape of the particle causes two different dipoles to form when interacting with light. The transverse dipole (diameter) and the longitudinal dipole (length) account for the oscillating electrons throughout the particle. The dipole interactions affect the optical properties of the particles. GNR LSP illustration Optical properties of GNRs The aspect ratio (A.R) is defined as the length over the diameter of the Gold nanorod (GNR). The shape of the particle causes the absorption and light scattering spectrum to have two peaks: longitudinal and transverse. The interaction between these two dipoles causes the longitudinal peak to be observed in the visible to NIR region. The longitudinal peak is much more intense than the transverse peak and can be tuned by changing the aspect ratio of the gold nanorods. As the A.R of the gold nanorods is increased, the longitudinal peak shifts into the NIR region. The optical properties of GNRs have been successfully modelled using Gans theory and Discrete Dipole Approximation (DDA). Two equations were derived using the two theories to output the longitudinal peak wavelength by inputting a given aspect ratio. GANS THEORY DDA The two equations can predict the A.R of GNRs using absorption data collected from the UV-Vis-NIR spectrophotometer. The equations can give preliminary estimation of the A.R before observing the particles on a TEM. Figure 11 displays the absorption data, estimated A.R from theory, and a visual representation for a set of GNRs with different aspect ratios. The tunable optical properties of the GNRs make them very desirable for a wide range of applications. The visible representation shows a colour shift as the A.R changes. Visual representation of different shapes and sizes of GNRs Normalised absorption of the particles

Sunday, January 19, 2020

The Shogun Dynasty :: Chinese China History

The term Shogun means general. Later, it refered to the leader of the Shogunate (Samurai's government). From 1192-1867, the Shogun ruled Japan. The Emperor reigned but did not rule. The Shoguns were a type of warlords that governed providences and states as a type of Japanese check and balance of the 16th century. The name of that form of government was called Shogunate. The Shogunates ruled as a military dictatorship for over a span of almost 700 years: they fought the Mongolians in 1281, fought in a civil war during 1467-1477, fought for Osaka in 1615, and saw Commodore Perry in 1853. The samurai are one of the most reconizable and most renowned warriors of the ancient times. They were members of a unique military class called the Japanese warriors. They emereged and grew more and more important during the Heian period (794-1185) when powerfull land owners hired them for their personal saftey and protection of their property. In the later times of the Heian period the most powerful military families, the Minamoto and Taira, had taken over political power over Japan and fought wars and battles for supremacy. When shogun Minamoto Yoritomo established a new government in Kamakura in 1192, the shogun (the highest military officer) became the ruler of Japan. The samurai were pinacled at the top of the social hierarchy and had many privilages. On the other hand, they were supposed to set a good example for the lower classes by following the principles of Bushido (the way of the warrior). The samurai's most important principles or duties were to be loyal to his master, use self-discipline and respect and also to use ethical behaviour. After a defeat or other dishonourable event many of the saurai chose to commit suicide by cutting their abdomen with a sword in order to preserve their honour. Such ritual suicide is called seppuku or harakiri. During the Edo period, which was mainly a peaceful time, most samurai had no motive or need to fight or do battle. In light of their situation many of the samurai chose to dedicate themselves to intellectual studies such as literature, history or the tea ceremony. In the 17th century, masterless and unemployed samurai caused some problems to the government because of their increased intellect. After the Meiji Restoration (1868), the samurai class dissapeared. The samurai sword, the katana, is still today the distinguishing mark of the samurai.

Saturday, January 11, 2020

Marilyn Monroe

As far as advertising goes, It was near perfect In Its tragedy to touch on the readers' subconscious senses of trust, logic, and emotion. This technique was developed by Aristotle and known as Rhetoric and Is delved Into three means of persuasion: Logos, Ethos, and Pathos. Logos Is the appeal to a person's logic and reason. Ethos is the appeal to a person's trust through credibility and trust. Pathos is the appeal to the person's emotions. This strategy is used in advertising to persuade the consumer to buy their product over another.This vintage 1986 Maxwell tape ad effectively used all three points of Aristotle Appeals with the SE of a statistic to satisfy the reader's logic (Logos), Marilyn Monomer's iconic status to appeal to the reader's sense of credibility (Ethos), and Marilyn Monomer's beauty, sex appeal, and charisma to incite an emotional response appealing to the viewer's feelings (Pathos). Let's begin with the ad's success in appealing to one's logic, or the Logos categor y. The ad uses a statistic stating that their tapes â€Å"†¦ Are manufactured up to 60% above industry standards. This statistic confirms the product's quality and gives some sound science to the consumer. It's a statistic, a number. People generally trust numbers. The statistic assures you that their product is manufactured over and above the industry standard and implies that all other brands are manufacture at bare requirements and no more. The consumer can feel confidence in the Maxwell brand because it's scientifically validated. It's logical and effectively appeals to the reader's sense of reason. Secondly, the market team utilized Marilyn Monomer's stardom and popularity to bring credibility to their claim and appeal to the reader's Ethos.Marilyn Monroe was still extremely popular at this time and her reputation was solid and reliable. 2012 marks 50 years after her death and she continues to be a major figure in the world of cinema and Is still acknowledged and respecte d. This year she Is the official icon of the 2012 Cannes Film Festival and honored on the event poster. The poster for the event has a picture of Marilyn seductively blowing out a single candle on a white cake. The poster, Like the picture In the Maxwell ad, captures her elegance and beauty. It Is recognizable and timeless.The consumer Is assured wrought her reliability, and her status and popularity appeal to the readers sense of credibility. Third Is the ads strongest pull, and It Is Its appeal to the viewer's emotions, Pathos. Marilyn Monroe Is loved and adored by so many people and the advertisers knew they could bank on this. Part of what people loved so much about simple photograph. But many adored her story too. Marilyn Monroe had a touching and inspirational story. Marilyn Monroe was born Norma Jeanne Morton in the charity ward at the Los Angles County Hospital.Her childhood was shaped by instability and she was passed from family member to family member, and even frequently lived in orphanages. In 1945 a photographer took notice of her and took her picture. Months later she was modeling for the covers of dozens of successful magazines and her life was changed forever. She had an uncanny ability to capture the hearts and attention of America and has remained loved even decades after her demise. Her photographs, like the one in the ad, still incite an emotional response. And lastly, let's not forget her sex appeal.Sex appeal was used in this add and is a ajar method used in selling products then and now. This ad concentrated on her stardom, but also played on her sex appeal too. Using words like â€Å"delicious dessert† and â€Å"the very best part of every man's fantasy'. I wonder if the advertiser's strategy could have been improved by focusing more on her film's successes and her success as an actress. The product Maxwell was selling was mainly for movies and many of the consumers would have been women. Could some of the more conservative con sumers been turned off by this approach? The ad was still brilliant and effectively used all aspects of persuasion.. Marilyn Monroe As far as advertising goes, It was near perfect In Its tragedy to touch on the readers' subconscious senses of trust, logic, and emotion. This technique was developed by Aristotle and known as Rhetoric and Is delved Into three means of persuasion: Logos, Ethos, and Pathos. Logos Is the appeal to a person's logic and reason. Ethos is the appeal to a person's trust through credibility and trust. Pathos is the appeal to the person's emotions. This strategy is used in advertising to persuade the consumer to buy their product over another.This vintage 1986 Maxwell tape ad effectively used all three points of Aristotle Appeals with the SE of a statistic to satisfy the reader's logic (Logos), Marilyn Monomer's iconic status to appeal to the reader's sense of credibility (Ethos), and Marilyn Monomer's beauty, sex appeal, and charisma to incite an emotional response appealing to the viewer's feelings (Pathos). Let's begin with the ad's success in appealing to one's logic, or the Logos categor y. The ad uses a statistic stating that their tapes â€Å"†¦ Are manufactured up to 60% above industry standards. This statistic confirms the product's quality and gives some sound science to the consumer. It's a statistic, a number. People generally trust numbers. The statistic assures you that their product is manufactured over and above the industry standard and implies that all other brands are manufacture at bare requirements and no more. The consumer can feel confidence in the Maxwell brand because it's scientifically validated. It's logical and effectively appeals to the reader's sense of reason. Secondly, the market team utilized Marilyn Monomer's stardom and popularity to bring credibility to their claim and appeal to the reader's Ethos.Marilyn Monroe was still extremely popular at this time and her reputation was solid and reliable. 2012 marks 50 years after her death and she continues to be a major figure in the world of cinema and Is still acknowledged and respecte d. This year she Is the official icon of the 2012 Cannes Film Festival and honored on the event poster. The poster for the event has a picture of Marilyn seductively blowing out a single candle on a white cake. The poster, Like the picture In the Maxwell ad, captures her elegance and beauty. It Is recognizable and timeless.The consumer Is assured wrought her reliability, and her status and popularity appeal to the readers sense of credibility. Third Is the ads strongest pull, and It Is Its appeal to the viewer's emotions, Pathos. Marilyn Monroe Is loved and adored by so many people and the advertisers knew they could bank on this. Part of what people loved so much about simple photograph. But many adored her story too. Marilyn Monroe had a touching and inspirational story. Marilyn Monroe was born Norma Jeanne Morton in the charity ward at the Los Angles County Hospital.Her childhood was shaped by instability and she was passed from family member to family member, and even frequently lived in orphanages. In 1945 a photographer took notice of her and took her picture. Months later she was modeling for the covers of dozens of successful magazines and her life was changed forever. She had an uncanny ability to capture the hearts and attention of America and has remained loved even decades after her demise. Her photographs, like the one in the ad, still incite an emotional response. And lastly, let's not forget her sex appeal.Sex appeal was used in this add and is a ajar method used in selling products then and now. This ad concentrated on her stardom, but also played on her sex appeal too. Using words like â€Å"delicious dessert† and â€Å"the very best part of every man's fantasy'. I wonder if the advertiser's strategy could have been improved by focusing more on her film's successes and her success as an actress. The product Maxwell was selling was mainly for movies and many of the consumers would have been women. Could some of the more conservative con sumers been turned off by this approach? The ad was still brilliant and effectively used all aspects of persuasion..

Friday, January 3, 2020

Nuclear Threats From North Korea - 1561 Words

Nuclear Threats from North Korea Describing the current issue: Isolated, underdeveloped, and strictly controlled by a regime, North Korea stands as the only totalitarian state to have survived a change in leadership (Behind the Wall†¦, 2012). North Korea maintains their control and power over the people through many different techniques: stranglehold on information, secret police, concentration camps, and control of the country’s economy. However there is one other factor that drives great fear into its people and the world; their development of nuclear weapons along with their propaganda techniques. On March 3rd, 2016, just last Thursday, North Korea under the direct order of Kim Jong Un, â€Å"fired short-range projectiles into the sea† to express their anger over the recent adoption of harsh U.N. sanctions (North Korea makes†¦, 2016). The following day, the Supreme leader â€Å"ordered his military on standby for nuclear strikes at any time† in order to â€Å"ramp-up propaganda pu sh in the face of what it portrays as an effort by South Korea and the U.S to overthrow its leadership† (North Korea makes†¦, 2016). All these threats of nuclear weapons and the North Korea’s slay approach on launching their bombs have created a uproar throughout the world. National Public Radio recorded all the responses of other countries and their representative of leadership who spoke out to the Nuclear threats they received by North Korea. By launching their hydrogen bombs, North Korea clearly violatedShow MoreRelatedNorth Korea Has No Ambition for Nuclear Proliferation Essay examples1467 Words   |  6 Pages There has been an increase in the support of taking forceful actions towards North Korea which has seemed to be unpredictable in its steps and decision taken especially in terms of security. 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North Korea’s nuclear programs have been a concern to America since their establishment, and even though tensions had lessened at points, nuclear proliferation is still a large issue. Due to America’s stance with North Korea, talksRead MoreInternational Law And Nuclear Weapons1568 Words   |  7 PagesInternationally, nuclear weapons have been an important topic of concern and debate for the past several decades. The concerns and debates within the international community regarding the proliferation of nuclear weapons to more sovereign states in the post-Cold War era have led to many international law instruments in attempts to contain these weapons of mass destruction. Treaties such as the Treaty on the Non-Proliferation of Nuclear Wea pons and the Test Ban Treaty of 1963, international organizationsRead MoreThe Struggle For Nuclear Power1485 Words   |  6 Pagesexample of this in today’s world is the struggle for nuclear power. Nuclear weapons were first developed in the United States in 1942 in what was called the Manhattan Project. Three years later, the US tested their first nuclear weapon in New Mexico, and a month later dropped two atomic bombs on the city of Hiroshima and Nagasaki in Japan, killing more than 220,000 civilians. Four years later the Soviet Union began successfully testing their own nuclear weapons, and China was soon to follow. In totalRead MoreNorth Korea s Nuclear Weapons1274 Words   |  6 Pagesto the Korean War, North Korea has insisted its demand for nuclear weapons. North Korean leaders and officials claim this right on the basis to safeguard North Korea’s dignity, sovereignty and ensure peace in its nation. Since its withdrawal from the Nuclear Non-Proliferation Tre aty (NPT) in January 2003, North Korea has demonstrated unacceptable behavior violating its obligations, in order to progress its nuclear weapon program. The United States views North Korea’s nuclear expansion behavior